Protein Alignment CG11313 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 85/312 - (27%)
• Similarity: 127/312 - (40%)
• Gaps: 50/312 - (16%)

  Fly    60 IRESRCLVSDQSDLPFVCCTPDTDYNTTRARPNDEVIHSTLLPDRSICGGDIAYNQITKGNETVL 124
            ||..|.|..:.|.:.....:..|...|.:|.....|:             .:..|:|..|.....
Human   147 IRNLRALPINASSVQVNAMSSSTGELTVQASCGKRVV-------------PLNVNRIASGVIAPK 198

  Fly   125 TEFAWMVLLEY-RPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNT 188
            ..:.|...|:| ..|.       |..:||:|.::||||||........:..|||...:.
Human   199 AAWPWQASLQYDNIHQ-------CGATLISNTWLVTAAHCFQKYKNPHQWTVSFGTKIN------ 250

  Fly   189 SAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQ 253
                        |..::..|....|||.:.:.....|||:::::..|.:|..||.:|||....
Human   251 ------------PPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASA-- 301

  Fly   254 NWQSGQAFTVAGWGRT-LTSESSPVKMKLRVTYVEPGLCRRK--YASIVVLGDSHLCAEGRSRG- 314
            ::|......:.|:|.. ...||.....:.||..:...:|::.  |.:.:..|  ..|| |...|
Human   302 SFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPG--MFCA-GYMEGI 363

  Fly   315 -DSCDGDSGGPLMAFH-EGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWI 364
             |:|.|||||||:... :..|.|.||||:|.|||.:..|.|||.|..|..||
Human   364 YDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440	5/17 (29%)
		Tryp_SPc	116..367	CDD:238113	75/256 (29%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188	1/1 (100%)
		Tryp_SPc	190..418	CDD:238113	75/256 (29%)