Protein Alignment CG11313 and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 94/375 - (25%)
• Similarity: 150/375 - (40%)
• Gaps: 87/375 - (23%)

  Fly     7 VLLCLLIIRTAHGQYVSCRNP-----------NQRTGYCVNIPLCVPLNSVLAKSNPTDSEMRFI 60
            ||..:|:|...|    |..:|           :::....|..|...|.:..:.|.|.|::: .::
Human   115 VLAHMLLICRFH----STEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETD-SYL 174

  Fly    61 RESRCLVSDQSDLPFVCCTPDTDYNTTRARPNDEVIHSTLLPDRSICGGDIAYNQITKGNETVLT 125
            ..              ||      .|.|::        ||.....|.||    .::.:|
Human   175 NH--------------CC------GTRRSK--------TLGQSLRIVGG----TEVEEG------ 201

  Fly   126 EFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSA 190
            |:.|...|::   ||..   .|..:|||..::|:||||.:......:...||.|:::
Human   202 EWPWQASLQW---DGSH---RCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIK-------- 252

  Fly   191 VVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNW 255
                      |..::..:..|.:||.:.......||:|..|:..|.|:.::..||||.  ....:
Human   253 ----------PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD--ASYEF 305

  Fly   256 QSGQAFTVAGWGRTLTSESSPVKMK-LRVTYVEPGLCRRKYASIVVLGDSHLCA---EGRSRGDS 316
            |.|....|.|:|.......|...:: .:||.::...|....|....:....|||   ||::  |:
Human   306 QPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKT--DA 368

  Fly   317 CDGDSGGPLMAFH-EGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWIT 365
            |.|||||||::.. ..:|.|.||||:|..|.....|.|||.|.:...|||
Human   369 CQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWIT 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440	7/64 (11%)
		Tryp_SPc	116..367	CDD:238113	72/255 (28%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	7/35 (20%)
		Tryp_SPc	192..420	CDD:238113	75/265 (28%)