DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11313 and TPSG1

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	XP_011520748.1	Gene:	TPSG1 / 25823	HGNCID:	14134	Length:	346	Species:	Homo sapiens

Alignment Length:	282	Identity:	95/282 - (33%)
Similarity:	121/282 - (42%)	Gaps:	56/282 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTY-CAGSLINNRYVVTAAHCVS 165
            |..|..||     :|..|:......:.|...|..|       |.: |.|||::.::|:|||||.|
Human    54 PQVSDAGG-----RIVGGHAAPAGAWPWQASLRLR-------RVHVCGGSLLSPQWVLTAAHCFS 106

  Fly   166 AATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHES----FGTRLFWNDI 226
            .:..      |....|.|||...:.           .|....|.:|.:|.|    .||.   .||
Human   107 GSLN------SSDYQVHLGELEITL-----------SPHFSTVRQIILHSSPSGQPGTS---GDI 151

  Fly   227 ALIRLAREVAYSPSIRPVCLPST-----VGLQNWQSGQAFTVAGWGRTLTSESSPVKMKLR---V 283
            ||:.|:..|..|..|.|||||..     .|::.|       |.|||.|...|..|....||   |
Human   152 ALVELSVPVTLSSRILPVCLPEASDDFCPGIRCW-------VTGWGYTREGEPLPPPYSLREVKV 209

  Fly   284 TYVEPGLCRRKYASI--VVLGDSHLCAEGRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCG 346
            :.|:...|||.|...  .:|....|||.|  .||:|..||||||:....|.||..|.||:|..||
Human   210 SVVDTETCRRDYPGPGGSILQPDMLCARG--PGDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCG 272

  Fly   347 SRFWPAVYTNVLSYETWITQNI 368
            ....|.|||.|.:|..||.::|
Human   273 RPNRPGVYTRVPAYVNWIRRHI 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	90/265 (34%)
		Tryp_SPc	116..364	CDD:214473	88/262 (34%)
TPSG1	XP_011520748.1	Tryp_SPc	62..290	CDD:214473	88/263 (33%)
TPSG1	XP_011520748.1	Tryp_SPc	63..293	CDD:238113	90/265 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840