DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11313 and svh-1

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	430	Identity:	110/430 - (25%)
Similarity:	165/430 - (38%)	Gaps:	131/430 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CLLIIRTAHGQYVSCR----------------NPNQRTGYCVNI------PLCVP-LNSVLAKSN 51
            |:...:..:|| :.|:                |.:..:||...:      |:|.. ||..:  ||
Worm   571 CIRFDQLCNGQ-IDCQSGEDEDYCRANSFRLTNGSDTSGYLEVLFRSRWEPICADHLNGKI--SN 632

  Fly    52 PTDSEMR-----FIRESRCLVSDQSDLPFVCCTPDTDYN-----TTRARPNDEVIHSTLLPDRSI 106
            .....||     ||..:...:|...:   |.|..|....     |..||.:  .|....:...|.
Worm   633 SICDAMRLGEHGFILSTNATISSGYN---VNCDVDCSIRRSSSCTRHARIS--CISQNGMSSASQ 692

  Fly   107 CG--------GDIAYNQITK---GNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTA 160
            ||        .|.|.::|.:   |.|||...|.|...|..:.....    :|..|:::..:::||
Worm   693 CGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKATKAH----HCGASILDKTHLITA 753

  Fly   161 AHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEI----RIH-ESFGTR 220
            |||.....|..    |:.|.|...::|.:      :|.          |:|    ||| ......
Worm   754 AHCFEEDERVS----SYEVVVGDWDNNQT------DGN----------EQIFYLQRIHFYPLYKD 798

  Fly   221 LFWNDIALIRLAREVAYSPSI------RPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESSPVKM 279
            :|.:|||::    |:.| |.|      :|:||||...:  :..|:...|:|||          .|
Worm   799 IFSHDIAIL----EIPY-PGIEFNEYAQPICLPSKDFV--YTPGRQCVVSGWG----------SM 846

  Fly   280 KLRVTYVEPGLCRRKYASIV----------------VLGDSHLCAEGRSRG--DSCDGDSGGPLM 326
            .||  |.|     |..|:::                .:..|..|| |...|  |||.||||||..
Worm   847 GLR--YAE-----RLQAALIPIINRFDCVNSSQIYSSMSRSAFCA-GYLEGGIDSCQGDSGGPFA 903

  Fly   327 AFHE-GVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWIT 365
            ...| |.:||.|::|:|..|..:..|.:||.|..|.:||:
Worm   904 CRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWIS 943

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855	16/81 (20%)
		Tryp_SPc	116..367	CDD:238113	80/283 (28%)
		Tryp_SPc	116..364	CDD:214473	78/280 (28%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566	4/19 (21%)
		SRCR_2	599..681	CDD:382996	20/88 (23%)
		Tryp_SPc	713..945	CDD:238113	79/280 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000