DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11313 and Klk1b5

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_032482.1	Gene:	Klk1b5 / 16622	MGIID:	892020	Length:	261	Species:	Mus musculus

Alignment Length:	230	Identity:	65/230 - (28%)
Similarity:	101/230 - (43%)	Gaps:	30/230 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 CAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEI 211
            |.|.|:|..:|:|||||.:...:...|..:|.......:|.       |..:.:|.| ...:..:
Mouse    50 CGGVLLNANWVLTAAHCHNDKYQVWLGKNNFFEDEPSAQHR-------LVSKAIPHP-DFNMSLL 106

  Fly   212 RIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESSP 276
            ..|.......:.||:.|:||.:....:..::|:.||:    :..:.|.....:|||........|
Mouse   107 NEHTPQPEDDYSNDLMLLRLKKPADITDVVKPIDLPT----EEPKLGSTCLASGWGSITPVIYEP 167

  Fly   277 ------VKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG-DSCDGDSGGPLMAFHEGVWV 334
                  |..||    :....|.:  |.|..:.|..|||.....| |:|.|||||||:.  :|  |
Mouse   168 ADDLQCVNFKL----LPNEDCVK--AHIEKVTDVMLCAGDMDGGKDTCMGDSGGPLIC--DG--V 222

  Fly   335 LGGIVSFGLN-CGSRFWPAVYTNVLSYETWITQNI 368
            |.||.|:|.: ||....|.:||.::.:.:||...|
Mouse   223 LHGITSWGPSPCGKPNVPGIYTKLIKFNSWIKDTI 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	64/227 (28%)
		Tryp_SPc	116..364	CDD:214473	62/224 (28%)
Klk1b5	NP_032482.1	Tryp_SPc	24..253	CDD:214473	62/224 (28%)
Klk1b5	NP_032482.1	Tryp_SPc	25..256	CDD:238113	64/227 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910