DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11313 and Prss29

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_444490.2	Gene:	Prss29 / 114662	MGIID:	2149952	Length:	279	Species:	Mus musculus

Alignment Length:	277	Identity:	91/277 - (32%)
Similarity:	130/277 - (46%)	Gaps:	54/277 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 ITKGNETVLTEFAWMVLLEYRPHDGQQLRTY----------CAGSLINNRYVVTAAHCVSAATRA 170
            |..|:.....::.|.|          .||.|          |.||:|:.::|:|||||:    |.
Mouse    31 IVGGHSAPQGKWPWQV----------SLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCI----RE 81

  Fly   171 RKGDVS-FRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLARE 234
            |..|.| ||  :|:||      .....|:.|     ::|..:.||..|......:|:||::||..
Mouse    82 RDADPSVFR--IRVGE------AYLYGGKEL-----LSVSRVIIHPDFVHAGLGSDVALLQLAVS 133

  Fly   235 VAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESSPVKMKL---RVTYVEPGLCRRKYA 296
            |...|:::||.|||. .|:..:....: |.|||...|..|.|...:|   :|..::..||...|.
Mouse   134 VQSFPNVKPVKLPSE-SLEVTKKDVCW-VTGWGAVSTHRSLPPPYRLQQVQVKIIDNSLCEEMYH 196

  Fly   297 SI---------VVLGDSHLCAEGRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPA 352
            :.         ::|.|. ||| |....|||.|||||||:....|.|.|.|:||:|..|..|.:|.
Mouse   197 NATRHRNRGQKLILKDM-LCA-GNQGQDSCYGDSGGPLVCNVTGSWTLVGVVSWGYGCALRDFPG 259

  Fly   353 VYTNVLSYETWITQNIR 369
            ||..|.|:..||||.::
Mouse   260 VYARVQSFLPWITQQMQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	90/273 (33%)
		Tryp_SPc	116..364	CDD:214473	87/270 (32%)
Prss29	NP_444490.2	Tryp_SPc	31..274	CDD:238113	90/273 (33%)
Prss29	NP_444490.2	Tryp_SPc	31..271	CDD:214473	87/270 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930