Protein Alignment CG11313 and KLK8

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 117/259 - (45%)
• Gaps: 64/259 - (24%)

  Fly   134 EYRPH---------DGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTS 189
            |.:||         .||||  .|.|.|:...:|:|||||...           :.:||||:|:
Human    83 ECQPHSQPWQAALFQGQQL--LCGGVLVGGNWVLTAAHCKKP-----------KYTVRLGDHS-- 132

  Fly   190 AVVDCLNGRCLPE---PVQIAV-------EEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPV 244
                 |..:..||   ||..::       .::..|.        :|:.|::|..:.:....::|:
Human   133 -----LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHN--------HDLMLLQLRDQASLGSKVKPI 184

  Fly   245 CLPSTVGLQNWQSGQAFTVAGWGRTLTS--ESSPVKMKLRVTYVEP-GLCRRKYASIVVLGDSHL 306
            .|..    ...|.||..||:||| |:||  |:.|..:......:.| ..|...|...:.  |..:
Human   185 SLAD----HCTQPGQKCTVSGWG-TVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQIT--DGMV 242

  Fly   307 CAEGRSRG-DSCDGDSGGPLMAFHEGVWVLGGIVSFGLN-CGSRFWPAVYTNVLSYETWITQNI 368
            || |.|:| |:|.|||||||:.  :|  .|.||.|:|.: ||....|.||||:..|..||.:.|
Human   243 CA-GSSKGADTCQGDSGGPLVC--DG--ALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	79/256 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	77/253 (30%)