Protein Alignment CG11313 and KLK11

DIOPT Version :10

• Sequence 1: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 129/298 - (43%)
• Gaps: 73/298 - (24%)

  Fly   106 ICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDG-------QQLRTYCAGSLINNRYVVTAAHC 163
            :.||:   .:|.||             .|.:||..       ::.|..|..:||..|:::|||||
Human    47 LVGGE---TRIIKG-------------FECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHC 95

  Fly   164 ----VSAATRAR-KGDVS---------FRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIH 214
                ||..:... ..|:|         .|..|.||:||......|       |..:.|.|... |
Human    96 LKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGC-------EQTRTATESFP-H 152

  Fly   215 ESFGTRL----FWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESS 275
            ..|...|    ..|||.|:::|..|:.:.::||:.|.|    :...:|.:..::|||.|    ||
Human   153 PGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSS----RCVTAGTSCLISGWGST----SS 209

  Fly   276 PVKMKL-------RVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG-DSCDGDSGGPLMAFHEGV 332
            | :::|       .:|.:|...|...|...:.  |:.:||..:..| |||.|||||||:....
Human   210 P-QLRLPHTLRCANITIIEHQKCENAYPGNIT--DTMVCASVQEGGKDSCQGDSGGPLVCNQS-- 269

  Fly   333 WVLGGIVSFGLN-CGSRFWPAVYTNVLSYETWITQNIR 369
              |.||:|:|.: |.....|.|||.|..|..||.:.::
Human   270 --LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMK 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	84/284 (30%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	82/282 (29%)