DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11313 and proc.2

DIOPT Version :9

Sequence 1:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	98/335 - (29%)
Similarity:	147/335 - (43%)	Gaps:	61/335 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PLNSVLAKSNPTDSEMRFIR--ESRCLVSDQSDLPFVCCTPDTDYNTTRARPNDEVIHSTLLPDR 104
            |:|......|...:.:|..|  .|:.:..:...|..|  .|| ||||               ||
Frog   386 PINKTSLDHNEIGASVRAARTGTSKSVWEENHGLASV--EPD-DYNT---------------PD- 431

  Fly   105 SICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATR 169
                ||:   :|..|....|.:..|.||:......|     :|.||||::|:|::||||.
Frog   432 ----GDV---RIVGGMRCELGQCPWQVLIRNNRGFG-----FCGGSLISSRWVLSAAHCF----- 479

  Fly   170 ARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLARE 234
              :..:...|::  |:::|..       |.:.|. :|||.::..|.::....:.:||||:.|...
Frog   480 --ESQIPHHVTI--GDYDTYR-------RDMDEQ-KIAVLQVFSHPNYLAEFYDHDIALLFLRSP 532

  Fly   235 VAYSPSIRPVCLPST-VGLQNWQSGQAFTVAGWGRTLTSESSPVK---MKLRVTYVEPGLCRRKY 295
            ..:....||:|||:. :|....|.||...|:|||  .|.:..|..   :|:|:..|....|....
Frog   533 AMFGEYSRPICLPNPGLGKMLTQEGQTGQVSGWG--ATRQFGPYTRFLLKVRLPIVSQETCMAST 595

  Fly   296 ASIVVLGDSHLCAEGRSRG--DSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVL 358
            .:|  |..:..|| |...|  |:|.||||||........|.|.|:||:|..|..:....|||.|.
Frog   596 ENI--LTGNMFCA-GYKEGVKDACSGDSGGPFAVLFHDTWFLVGVVSWGDGCAEKGKYGVYTRVA 657

  Fly   359 SYETWITQNI 368
            :|..||.:.|
Frog   658 NYMPWIKETI 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11313	NP_651821.3	CLIP	24..78	CDD:288855	8/37 (22%)
		Tryp_SPc	116..367	CDD:238113	79/256 (31%)
		Tryp_SPc	116..364	CDD:214473	77/253 (30%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	79/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920