DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4H2 and NUC-L1

DIOPT Version :10

Sequence 1:NP_651820.1 Gene:eIF4H2 / 43645 FlyBaseID:FBgn0039797 Length:459 Species:Drosophila melanogaster
Sequence 2:NP_175322.1 Gene:NUC-L1 / 841314 AraportID:AT1G48920 Length:557 Species:Arabidopsis thaliana


Alignment Length:391 Identity:97/391 - (24%)
Similarity:147/391 - (37%) Gaps:106/391 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 ANRSSQRDREFNRDNTYNNNRDNRDHNRDNRDNRENRSNFQNYRNRDRDRDRQRQVPTEPPF--- 63
            |::.|..|         .::....|.:.|..:..:.:|:.....:.::...:|.:.|:.|..   
plant   241 ASKKSSSD---------ESSESEEDESEDEEETPKKKSSDVEMVDAEKSSAKQPKTPSTPAAGGS 296

  Fly    64 -IAYVGNLPKGLVQGDVMKIFSDF-EVKNVRLIKDRETDEFKGYGYVEFETLAQLKSALNCNGRI 126
             ..:..||...:.:.||...|.:. ||.:||...:|:...|:|:|:|||.:..:.:.||..:||.
plant   297 KTLFAANLSFNIERADVENFFKEAGEVVDVRFSTNRDDGSFRGFGHVEFASSEEAQKALEFHGRP 361

  Fly   127 KLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGV---GHERGGGVGRGGSTGAANGNNPYYQRR 188
            .|   ...:|:|||..|        |..|..||..   |:.|.||.|         |:......:
plant   362 LL---GREIRLDIAQER--------GERGERPAFTPQSGNFRSGGDG---------GDEKKIFVK 406

  Fly   189 NYRRDDSVGSHQFRRREPRSNSSNHQMSNSS-----PTQSTTSINYNRTTRGGFNSRVAVGGNGN 248
            .:  |.|:.....:.......||..::.|.|     .|.::..|.|...:.|   ...|:..||:
plant   407 GF--DASLSEDDIKNTLREHFSSCGEIKNVSVPIDRDTGNSKGIAYLEFSEG---KEKALELNGS 466

  Fly   249 RYQGG------APRNFNDREDQQSTGSGGFQRNRTYNFNRSMNNSVGGGGAGVGRGGHPQRNFNG 307
            ...||      .||...|     |:|.|||.|.         |...|.||   |||        .
plant   467 DMGGGFYLVVDEPRPRGD-----SSGGGGFGRG---------NGRFGSGG---GRG--------R 506

  Fly   308 NGGGGGFGVVNGGGNYTNFVQNRNRD-RRGHYNPNHSGSSGGYNNN------------GNNTFGG 359
            :||.|.||  :|||        |.|| .||.:     ||.||..::            ...|||.
plant   507 DGGRGRFG--SGGG--------RGRDGGRGRF-----GSGGGRGSDRGRGRPSFTPQGKKTTFGD 556

  Fly   360 E 360
            |
plant   557 E 557

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4H2NP_651820.1 RRM_SF 58..144 CDD:473069 27/90 (30%)
NUC-L1NP_175322.1 RRM1_NUCLs 298..375 CDD:409884 25/79 (32%)
RRM2_NUCLs 402..479 CDD:409885 15/81 (19%)

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