Protein Alignment eIF4H2 and RBMX2

DIOPT Version :10

• Sequence 1: NP_651820.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_057108.2
• Gene: RBMX2 / 51634
• HGNCID: 24282
• Length: 322
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 52/219 - (23%)
• Similarity: 92/219 - (42%)
• Gaps: 36/219 - (16%)

  Fly    66 YVGNLPKGLVQGDVMKIFSDF-EVKNVRLIKDRETDEFKGYGYVEFETLAQLKSAL-NCNG-RIK 127
            ::|.||..|.:||::.:||.: |:.|:.|::|::|.:.||:.::.:|.......|: |.|| :||
Human    39 FLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIK 103

  Fly   128 --------LDNFSAPL-RIDIADHRRQNPGAPSGVGGAPPAGVGHERGGGVGRGGSTGAANGNNP 183
                    :.|:.||. ..:|.|..||.                .|:|.| .|..|...:..:..
Human   104 GRTIRVDHVSNYRAPKDSEEIDDVTRQL----------------QEKGCG-ARTPSPSLSESSED 151

  Fly   184 YYQRRNYRRDDSVGSHQFRRREPRSNS-SNHQMSNSSPTQSTTSINYNRTTRGGFNSRVAVGGNG 247
            ....:.:::|......:.:.:|..... ...|.|:|||.:.|.. ..:.|.....:|:     |.
Human   152 EKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVK-EKDDTGPKKHSSK-----NS 210

  Fly   248 NRYQGGAPRNFNDREDQQSTGSGG 271
            .|.|...||........::..|||
Human   211 ERAQKSEPREGQKLPKSRTAYSGG 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H2	NP_651820.1	RRM_SF	58..144	CDD:473069	27/89 (30%)
RBMX2	NP_057108.2	RRM_ist3_like	27..115	CDD:409845	22/75 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..322		22/108 (20%)