Protein Alignment eIF4H2 and eif4b

DIOPT Version :10

• Sequence 1: NP_651820.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: XP_012812217.1
• Gene: eif4b / 448618
• XenbaseID: XB-GENE-988676
• Length: 614
• Species: Xenopus tropicalis
• Alignment Length: 388
• Identity: 104/388 - (26%)
• Similarity: 149/388 - (38%)
• Gaps: 102/388 - (26%)

  Fly    47 RDRDRDRQRQVPTEPPFIAYVGNLPKGLVQGDVMKIFSDFEVKNVRLIKDRETDE-FKGYGYVEF 110
            |:.:.||.| :|..|||.|::||||..:.:..:.|.|....:..|||.::....| .||:||.||
 Frog    95 REPNVDRSR-LPKSPPFTAFLGNLPYDVTEESIQKFFRGLNISAVRLPREPSNPERLKGFGYAEF 158

  Fly   111 ETLAQLKSALNCNGRIKLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGVGHERGGGVGRGGST 175
            :.|..|..||:.|.. .|.|  ..:|:||||..:...              ..||..|..|.
 Frog   159 DDLDSLLRALSLNEE-SLGN--RRIRVDIADQAQDKD--------------RDERSFGRDRD--- 203

  Fly   176 GAANGNNPYYQRRNYRRDDSVGSHQFRRREPRSNSSNHQMSNSSPTQSTTSINYNRTTRGGFNSR 240
                        || |..|...|..:|.|....:..::.......:|.      :|.....:.|
 Frog   204 ------------RN-RESDKTDSSDWRARPSTDSFDDYPPRRGDDSQG------DRYRSDRYES- 248

  Fly   241 VAVGGNGNRYQGGAPRNFNDREDQQSTGSGGFQRNRTYNFNRSMNNSVGGGGAGVGRGGHPQRNF 305
                   :||:.| ||...||.::.........|||: :::|..::.  ||....|.|.....::
 Frog   249 -------DRYRDG-PRRDGDRYERDRGRDRYDDRNRS-DYDRGYDSR--GGRRAFGSGYRRDDDY 302

  Fly   306 NGNGGGGGFGVVNGGGNYTNFVQNRNRDRRGHYNPNHSGSSGGYNNNGNNTFGGENNHPVHGASE 370
            .|.||        ||..|.:..:.|..||...:|        ||:.|                .|
 Frog   303 RGGGG--------GGDRYGDRYEERREDRSDRWN--------GYSRN----------------EE 335

  Fly   371 SASSGTGPSSSNQFAVRDDDDRPKLVLKPRTVTAPINS----LAETKQAALIFGKAKPRDDSS 429
            ......||:           .||||.||||  |||.:.    .|.|.:||.|||.|||.|.::
 Frog   336 RREERAGPT-----------QRPKLNLKPR--TAPKDEEGGPSAATSRAASIFGGAKPVDTAA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H2	NP_651820.1	RRM_SF	58..144	CDD:473069	33/86 (38%)
eif4b	XP_012812217.1	RRM_eIF4B	108..189	CDD:409836	32/83 (39%)