Protein Alignment eIF4H2 and Eif4b

DIOPT Version :10

• Sequence 1: NP_651820.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001008325.1
• Gene: Eif4b / 300253
• RGDID: 1306479
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 400
• Identity: 92/400 - (23%)
• Similarity: 143/400 - (35%)
• Gaps: 126/400 - (31%)

  Fly    47 RDRDRDRQRQVPTEPPFIAYVGNLPKGLVQGDVMKIFSDFEVKNVRLIKD-RETDEFKGYGYVEF 110
            |:.:.||.| :|..||:.|::||||..:.:..:...|....:..|||.:: ...|..||:||.||
  Rat    81 REPNIDRSR-LPKSPPYTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLKGFGYAEF 144

  Fly   111 ETLAQLKSALNCNGRIKLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGVGHERGGGVGRGGST 175
            |.|..|.|||:.|.. .|.|  ..:|:|:||
  Rat   145 EDLDSLLSALSLNEE-SLGN--RRIRVDVAD---------------------------------- 172

  Fly   176 GAANGNNPYYQRRNYRRDDSVGSHQFRRREPRSNSSNHQMSNSSPTQSTTSINYNRTTRG--GFN 238
                      |.::..|||    ..|.|...|.:........:.|  :|.|.:.....||  .|.
  Rat   173 ----------QAQDKDRDD----RSFGRDRNRDSDKTDTDWRARP--ATDSFDDYPPRRGDDSFG 221

  Fly   239 SRVAVGGNGNRYQGGAPRNFND---REDQQSTGSGGFQRNRTYNFNRSMNNSVGGGGAGVGRGGH 300
            .:.......:||:.|....:.|   |:..:..|...:....:.:::|..::.:|.|....|.|..
  Rat   222 DKYRDRYESDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286

  Fly   301 PQRNFNGNGGGGGFGVVNGGGNYTNFVQNRNRDRRGHYNPNHSGSSGGYNNNGNNTFGGENNHPV 365
            ...::.|.|                   :|..||              |:...:.::...:::.
  Rat   287 RDDDYRGGG-------------------DRYEDR--------------YDRRDDRSWSSRDDYS- 317

  Fly   366 HGASESASSGTGPSSSNQFAVRDD---DD-----RPKLVLKPRTVTAPINSLAETKQ---AALIF 419
                                 |||   ||     ||||.||||:.....:|.|.|.|   ||.||
  Rat   318 ---------------------RDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSSRAASIF 361

  Fly   420 GKAKPRDDSS 429
            |.|||.|.::
  Rat   362 GGAKPVDTAA 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H2	NP_651820.1	RRM_SF	58..144	CDD:473069	32/86 (37%)
Eif4b	NP_001008325.1	RRM_eIF4B	94..175	CDD:409836	32/127 (25%)
		PRK12678	142..>294	CDD:237171	39/204 (19%)
		PTZ00108	<372..582	CDD:240271	92/399 (23%)