Protein Alignment eIF4H2 and H05C05.1

DIOPT Version :10

• Sequence 1: NP_651820.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001367918.1
• Gene: H05C05.1 / 259329
• WormBaseID: WBGene00019157
• Length: 903
• Species: Caenorhabditis elegans
• Alignment Length: 485
• Identity: 112/485 - (23%)
• Similarity: 173/485 - (35%)
• Gaps: 142/485 - (29%)

  Fly     7 QRDREFNRDNTYNNNRDNRDHNRDNRDNRENRSNFQNYRNRDRDRDRQRQVPTEPPFIAYVGNLP 71
            :.|.:||:   ..::.|......|..:..||.|         .:|..:|.:||||||...:.|:.
 Worm   104 EEDEQFNK---ITDDDDGETEEADGGETTENSS---------PERRGRRNIPTEPPFRVQITNIS 156

  Fly    72 KGLVQGDVMKIF-SDFEVKNVRLIKDRETDEFKGYGYVEFE-------TLAQLKSALNCNGRIKL 128
            ...|:.:::..| .:..:|.|.:.|:.        |..|||       .||..|..:...||: |
 Worm   157 SQHVEEELIYYFGGESHIKRVDIRKED--------GNAEFEYFTRDGLLLALKKQDVEFKGRV-L 212

  Fly   129 DNFSAPLRIDIA----DHRRQNPGAPSGVGGAPPAGVGHERGGGVGRGGSTGAANGNNPYYQRRN 189
            ..|....|..:|    .|.:|..|.|            :|...    ...:|.::..|  |:|.:
 Worm   213 KVFVRQNRESVARVTSRHSQQEYGRP------------YESND----SHFSGKSSSQN--YRRSH 259

  Fly   190 YRRDDSVGSHQFRRREPRSNSSNHQMSNSSPTQSTTSINYNRTTRGGFNSRVAVGGNGNRYQGGA 254
            |...:|:.|.:..|.: :.|.|||               |.....|||:.|    ..|..|:|..
 Worm   260 YNSQNSLNSDKHGRYD-KGNRSNH---------------YGTMPAGGFHDR----RGGGSYRGSN 304

  Fly   255 PRNFNDREDQQSTGSGGFQRNRTYNFNRSMNNSVG------GGGAGVGRGGHPQRNFNGNGGGGG 313
            ...||:        :|.|:..|..|::|  .||.|      |.|..:.|.|..|.|.|.:
 Worm   305 DCRFNN--------NGSFRAPRNPNYDR--QNSSGRDDYHHGNGGPLQRSGSYQHNHNHS----- 354

  Fly   314 FGVVNGGGNYTNFVQNRNRDRRGHYNPNHSGSSGGYNNNGNNTFGGENNHPVHGASESASSGTGP 378
             ...:.|..|:|         ..||:..|.|             ||..:......:||.|
 Worm   355 -NTKDYGRQYSN---------HNHYSNYHGG-------------GGPGSISARSRTESHS----- 391

  Fly   379 SSSNQFAVRDDDDRPKLVLKPRTVTAPINSLAETKQ------AALIFGKAKPRDDSS--TPVSSP 435
            :::|..|......|..|        |...::.||.|      .|..||.|||.|..:  ..:...
 Worm   392 TTNNYDAFSRTSSRMSL--------AATGTVEETPQRKSTGGGANPFGDAKPVDTETRLLELEKR 448

  Fly   436 RQDLD------AGSSGAPSDHDHDPGLGDN 459
            ||:.:      |.::.|.:....||..||:
 Worm   449 RQEKEKEQKAAAAAAAAAAAAAADPVAGDH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H2	NP_651820.1	RRM_SF	58..144	CDD:473069	26/97 (27%)
H05C05.1	NP_001367918.1	RRM_SF	143..220	CDD:473069	23/85 (27%)