Protein Alignment Pka-C2 and DBF20

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_015436.1
• Gene: DBF20 / 856227
• SGDID: S000006315
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 426
• Identity: 99/426 - (23%)
• Similarity: 181/426 - (42%)
• Gaps: 99/426 - (23%)

  Fly     3 QHTSQYVFNSKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITR--------------AVLGN 53
            |.|.| |....|....:.:..::...|.|     :.|...|:.:.|              ..:|.
Yeast   119 QRTKQ-VLRYLEQQRSVKNVSNKVLNEEW-----ALYLQREHEVLRKRRLKPKHKDFQILTQVGQ 177

  Fly    54 GSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYL 118
            |.:|.|.|.::|......|.|:::|:.|.:|.:..||..|:.:|...|..:|:.|:.:.:..:.|
Yeast   178 GGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESL 242

  Fly   119 YLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIK 183
            ||.:..|.||:..:.....|.....|||||.:::..|:..:|::...:|||||||.|:|..|:||
Yeast   243 YLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIK 307

  Fly   184 ITDFG----------------------------FTKR-VDGR--------------TSTLCGTPE 205
            :||||                            ||:| ::.|              .:::.|:|:
Yeast   308 LTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPD 372

  Fly   206 YLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLR 270
            |:|.|:::.:.|:.:||:|:.|.:::|.:.|.:||:..:.:               .:|  ..||
Yeast   373 YMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTN---------------ETY--ENLR 420

  Fly   271 SLVESLMQVDTSKRLGNSNDGSSD------------VKSHPWFQGVDWFGILNQEV----TAPYQ 319
            ...::|.:..|..|....:|.:.|            |:|....:.:.:|..:|.|.    :.|:.
Yeast   421 YWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRVRSFEQVRKMSYFAEINFETLRTSSPPFI 485

  Fly   320 PTISGAEDLSNFENF---EFKDRYKSRINRHPELFA 352
            |.:....|...|::|   |...:|.....|..:|.|
Yeast   486 PQLDDETDAGYFDDFTNEEDMAKYADVFKRQNKLSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	85/363 (23%)
DBF20	NP_015436.1	MobB_Sid2p-like	77..164	CDD:439271	10/50 (20%)
		STKc_Sid2p_like	157..539	CDD:270751	90/382 (24%)