DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C2 and prkacaa

DIOPT Version :9

Sequence 1:	NP_733397.2	Gene:	Pka-C2 / 43644	FlyBaseID:	FBgn0000274	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_021326630.1	Gene:	prkacaa / 564064	ZFINID:	ZDB-GENE-050114-6	Length:	389	Species:	Danio rerio

Alignment Length:	340	Identity:	156/340 - (45%)
Similarity:	221/340 - (65%)	Gaps:	3/340 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKE 79
            |....|.....:|.::|.:..|:. .:|:::.....||.||||.||||:.|....::|.|::.|:
Zfish    53 DVKEFLAKAKEDFLKKWENPAQNT-ASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQ 116

  Fly    80 DLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKH 144
            .:|:|||:.|..|||.:|.|..||||:.|..|.|....||:::..|.|||:||:.||:.:|:|.|
Zfish   117 KVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPH 181

  Fly   145 ARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAP 209
            |||||||:.|..||:|.:.|:||||||||:|:||:|||::|||||.|||.|||.|||||||||||
Zfish   182 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAP 246

  Fly   210 EIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVE 274
            ||:..:.|||:|||||.|:|:||..||..||...  ..|.:|.||.....:.||:|:|.|:.|:.
Zfish   247 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLR 309

  Fly   275 SLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFEFKDR 339
            :|:|||.:||.||..:|.:|:|.|.||...||..|..::|.||:.|...|..|.|||::::.::.
Zfish   310 NLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEI 374

  Fly   340 YKSRINRHPELFANF 354
            ..|...:..:.||.|
Zfish   375 RVSITEKCGKEFAEF 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	146/290 (50%)
prkacaa	XP_021326630.1	STKc_PKA	80..369	CDD:271111	146/290 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020