Protein Alignment Pka-C2 and prkacbb

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001030148.1
• Gene: prkacbb / 563147
• ZFINID: ZDB-GENE-050904-4
• Length: 351
• Species: Danio rerio
• Alignment Length: 344
• Identity: 161/344 - (46%)
• Similarity: 222/344 - (64%)
• Gaps: 3/344 - (0%)

  Fly    11 NSKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKM 75
            |..|.....|.....:|..:|....||. |.|:::..:..||.||||.|:||:.|:...|||.|:
Zfish    11 NELESVKEFLAKAKEDFLRKWESPQQST-TCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKV 74

  Fly    76 MSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKF 140
            :.|:.:|:||||.|..|||.:|.|..||||:.|..:.|....||:::..|.|||:||:.||:.:|
Zfish    75 LDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRF 139

  Fly   141 NEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPE 205
            :|.||||||||:.|..||:|.:.|:||||||||:|:||.|||::|||||.|||.|||.|||||||
Zfish   140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPE 204

  Fly   206 YLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLR 270
            ||||||:..:.|||:|||||.|:|:||..||..||...  ..|.:|.||.....:.||:|:|.|:
Zfish   205 YLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLK 267

  Fly   271 SLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFE 335
            .|:.:|:|||.:||.||..:|.:|:|:|.||...||..|..::|.||:.|...|..|.|||:::|
Zfish   268 DLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYE 332

  Fly   336 FKDRYKSRINRHPELFANF 354
            .:|...|...:..:.|:.|
Zfish   333 EEDIRVSVTEKCAKEFSEF 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	147/290 (51%)
prkacbb	NP_001030148.1	STKc_PKA	42..331	CDD:271111	147/290 (51%)