Protein Alignment Pka-C2 and PRKX

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_005035.1
• Gene: PRKX / 5613
• HGNCID: 9441
• Length: 358
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 141/321 - (43%)
• Similarity: 206/321 - (64%)
• Gaps: 4/321 - (1%)

  Fly    36 QSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAA 100
            :.|..:|:::.|.|.:|.|:||.|.||:||:.|:::|.|:||..|::||||..||||||.||...
Human    40 EPPVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEV 104

  Fly   101 RFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLM 165
            ..||||.|..:.....:||:::..|.|||||||.|...:|:.....||:|::..|:||:|...::
Human   105 SHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIV 169

  Fly   166 YRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILV 230
            ||||||||||||:.|:||:|||||.|::..||.||||||||||||::|.:.:.::|||||.|||:
Human   170 YRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILI 234

  Fly   231 YEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDV 295
            :|.::|..||...|...|  |.||.......|.:....::.|::.|:.||.::||||..:|::||
Human   235 FEMLSGFPPFFDDNPFGI--YQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDV 297

  Fly   296 KSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFEFKDRYKSR--INRHPELFANF 354
            |.|.||:.|||..:..:::..|..|.|:|..|.||||.:...|...:.  ..:..|:|.||
Human   298 KHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPENDWDTAAPVPQKDLEIFKNF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	134/290 (46%)
PRKX	NP_005035.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		STKc_PRKX_like	47..338	CDD:270763	134/292 (46%)