Protein Alignment Pka-C2 and PRKG2

DIOPT Version :9

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_016863902.1
• Gene: PRKG2 / 5593
• HGNCID: 9416
• Length: 774
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 117/328 - (35%)
• Similarity: 182/328 - (55%)
• Gaps: 35/328 - (10%)

  Fly    22 NMSREFEER--------W------------------NHQTQSPYTNLENYITRAVLGNGSFGTVM 60
            |::|:.|:|        |                  ...:.||:.|||   ..|.||.|.||.|.
Human   407 NLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLE---IIATLGVGGFGRVE 468

  Fly    61 LVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLV 125
            ||:.|:....:|.|.:.|:.:|..||..||::||.:|.....||::.|..:.|...|:|::|...
Human   469 LVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEAC 533

  Fly   126 NGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFT 190
            .||||:|..|....|:|..::|..|.|..|.:|:|::.::||||||||::||..||:|:.||||.
Human   534 LGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFA 598

  Fly   191 KRVDG--RTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSK 253
            |::..  :|.|.||||||:|||::..:.::.|||:|:.||||||.:.|..||:  ..|.::.|:.
Human   599 KKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFS--GVDQMMTYNL 661

  Fly   254 ICICDYKM--PSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTA 316
            |.....||  |...|.:...|:..|.:.:.::||||..:|.:|:|.|.|..|.:|.|:..:.:.:
Human   662 ILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPS 726

  Fly   317 PYQ 319
            |.|
Human   727 PLQ 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	108/281 (38%)
PRKG2	XP_016863902.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142889
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840