Protein Alignment Pka-C2 and PRKACB

DIOPT Version :9

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_891993.1
• Gene: PRKACB / 5567
• HGNCID: 9381
• Length: 398
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 164/353 - (46%)
• Similarity: 232/353 - (65%)
• Gaps: 7/353 - (1%)

  Fly     2 SQHTSQYVFNSKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKS 66
            |:||:.:..:.||    .|.....:|.::|.:.||: ...||::..:..||.||||.||||:.|:
Human    53 SEHTALWDRSMKE----FLAKAKEDFLKKWENPTQN-NAGLEDFERKKTLGTGSFGRVMLVKHKA 112

  Fly    67 GKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELF 131
            .:.|||.|::.|:.:|:|||:.|..|||.:|.|..||||:.|..:.|....||:::..|.|||:|
Human   113 TEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMF 177

  Fly   132 SYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGR 196
            |:.||:.:|:|.||||||||:.|..||:|.:.|:||||||||:|:|.:|||::|||||.|||.||
Human   178 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGR 242

  Fly   197 TSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKM 261
            |.|||||||||||||:..:.|||:|||||.|:|:||..||..||...  ..|.:|.||.....:.
Human   243 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRF 305

  Fly   262 PSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAE 326
            ||:|:|.|:.|:.:|:|||.:||.||..:|.||:|:|.||...||..|..::|.||:.|...|:.
Human   306 PSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 370

  Fly   327 DLSNFENFEFKDRYKSRINRHPELFANF 354
            |.|||:::|.:|...|...:..:.|..|
Human   371 DTSNFDDYEEEDIRVSITEKCAKEFGEF 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	148/290 (51%)
PRKACB	NP_891993.1	STKc_PKA	89..378	CDD:271111	148/290 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.810