DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C2 and Prkx

DIOPT Version :9

Sequence 1:	NP_733397.2	Gene:	Pka-C2 / 43644	FlyBaseID:	FBgn0000274	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001029135.1	Gene:	Prkx / 501563	RGDID:	1564076	Length:	358	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	144/337 - (42%)
Similarity:	209/337 - (62%)	Gaps:	13/337 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLK 85
            |.:.|...::..|       :|:::.|.|.:|.|:||.|.||:||:|:.|.|.|:||..|::|||
  Rat    32 DPLPRTSSQKEGH-------SLQDWDTIATVGTGTFGRVNLVKEKTGRRYCALKIMSIPDVIRLK 89

  Fly    86 QVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAA 150
            |..||.|||.||.....||||.|:.:.....:||:::..|.|||||:|.|...:|:...|.|||.
  Rat    90 QEQHVQNEKAVLKEINHPFLIKLLWTDHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVAAIFYAT 154

  Fly   151 QVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLR 215
            ::..|:||:|...::||||||||||||:.|:||:|||||.|::..||.||||||||||||::|.:
  Rat   155 EIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSK 219

  Fly   216 PYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVD 280
            .:.::|||||.|||::|.::|..||...|...|  |.||..|....|.......:.|::.|:.||
  Rat   220 GHGRAVDWWALGILIFEMLSGFPPFFDDNPFGI--YQKILACKIDFPRQLDFTSKDLIKKLLVVD 282

  Fly   281 TSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENF---EFKDRYKS 342
            .::||||..:|:.|:|.|.||:||:|..:..:::..|..|.:|...|:||||.:   |. |:..|
  Rat   283 RTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPKLSSDGDISNFETYPEGEL-DKTPS 346

  Fly   343 RINRHPELFANF 354
            ..:...|.|.||
  Rat   347 VSDEDLETFKNF 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	133/290 (46%)
Prkx	NP_001029135.1	PTZ00263	35..358	CDD:140289	141/332 (42%)
Prkx	NP_001029135.1	STKc_PRKX_like	47..338	CDD:270763	133/292 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920