Protein Alignment Pka-C2 and Rps6ka3

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_017457618.1
• Gene: Rps6ka3 / 501560
• RGDID: 1563860
• Length: 759
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 116/325 - (35%)
• Similarity: 182/325 - (56%)
• Gaps: 32/325 - (9%)

  Fly    50 VLGNGSFGTVMLVREKSG---KNYYAAKMMSK-----EDLVRLKQVAHVHNEKHVLNAARFPFLI 106
            |||.||||.|.||::.||   :..||.|::.|     .|.||.|.      |:.:|.....||::
  Rat    92 VLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKM------ERDILVEVNHPFIV 150

  Fly   107 YLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKP 171
            .|..:.:....|||||..:.||:||:...:...|.|:..:||.|::||||:::|.:.::||||||
  Rat   151 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKP 215

  Fly   172 ENILLDQRGYIKITDFGFTKRV---DGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEF 233
            ||||||:.|:||:||||.:|..   :.:..:.|||.||:|||:|..|.:.:|.|||:||:|::|.
  Rat   216 ENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEM 280

  Fly   234 VAGRSPFAIHNRD---VILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDV 295
            :.|..||...:|.   .:::.:|:     .||.:.:.:.:||:..|.:.:.:.|||...||..::
  Rat   281 LTGTLPFQGKDRKETMTMILKAKL-----GMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEI 340

  Fly   296 KSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFE-NFEFKDRYKS-----RINRHPELFANF 354
            |.|.:|..:||..:..:|:..|::|.....||...|: .|..|....|     ..|.| :||..|
  Rat   341 KRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAH-QLFRGF 404

  Fly   355  354
              Rat   405  404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	108/298 (36%)
Rps6ka3	XP_017457618.1	STKc_RSK_N	91..407	CDD:270734	116/325 (36%)
		STKc_RSK2_C	421..759	CDD:271078