Protein Alignment Pka-C2 and akt2

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_937789.1
• Gene: akt2 / 378972
• ZFINID: ZDB-GENE-031007-5
• Length: 479
• Species: Danio rerio
• Alignment Length: 362
• Identity: 129/362 - (35%)
• Similarity: 203/362 - (56%)
• Gaps: 36/362 - (9%)

  Fly    24 SREFEERWNHQTQSPYTN----LENYITRA-------------VLGNGSFGTVMLVREKSGKNYY 71
            |||.:|..:....||..|    :|..||::             :||.|:||.|:|||||:...||
Zfish   112 SREEDEPMDINFGSPGDNSLEGMEAAITKSRTKVTMSDFDYLKLLGKGTFGKVILVREKATGMYY 176

  Fly    72 AAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRR 136
            |.|::.||.::...:|||...|..||...|.|||..|..:.:..|.|..::...||||||.:..|
Zfish   177 AMKILRKEVIIAKDEVAHTITESRVLQNTRHPFLTTLKYAFQTRDRLCFVMEYANGGELFFHLSR 241

  Fly   137 VRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTS--- 198
            .|.|.|..||||.|::..||||:|...::|||||.||::||:.|:|||||||..|  :|.|:
Zfish   242 ERVFTEDRARFYGAEIVSALEYLHSKDVVYRDLKLENLMLDKDGHIKITDFGLCK--EGITNEAT 304

  Fly   199 --TLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKM 261
              |.||||||||||:::...|.::||||..|:::||.:.||.||  :|:|...::..|.:.:.:.
Zfish   305 MKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF--YNQDHERLFELILMEEIRF 367

  Fly   262 PSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAE 326
            |...:.:.::|:..|::.|..:|||...:.:.:|.:|.:|..::|..:|.:::..|::|.::...
Zfish   368 PRNLSPEAKALLAGLLKKDPKQRLGGGPEDAKEVMTHKFFNNMNWQDVLQKKLVPPFKPQVTSET 432

  Fly   327 DLSNFENFEF---------KDRYKSRINRHPELFANF 354
            |...|:: ||         .|:|.|.....|:...:|
Zfish   433 DTRYFDD-EFTAQTITVTPPDQYDSLDAEDPDTRTHF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	115/308 (37%)
akt2	NP_937789.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	154..476	CDD:173686	119/320 (37%)