Protein Alignment Pka-C2 and kin-1

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001368699.1
• Gene: kin-1 / 3565407
• WormBaseID: WBGene00002189
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 375
• Identity: 164/375 - (43%)
• Similarity: 230/375 - (61%)
• Gaps: 26/375 - (6%)

  Fly     2 SQHTSQYVFN-----SKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVML 61
            |.:.:..||:     :.|.....||....:|::||.:..|:. ..|:::.....||.||||.|||
 Worm   209 SDYNNAMVFSNGRLAAAETIKEFLDKAREDFKQRWENPAQNT-ACLDDFDRIKTLGTGSFGRVML 272

  Fly    62 VREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVN 126
            |:.|...||||.|::.|:.:|:||||.|..|||.:|.|..||||:.:..|.|....||::|..::
 Worm   273 VKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFIS 337

  Fly   127 GGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTK 191
            |||:||:.||:.:|:|.|:||||||:.||.||:|.:.|:||||||||:|:|..||:|||||||.|
 Worm   338 GGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAK 402

  Fly   192 RVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICI 256
            ||.|||.|||||||||||||:..:.|||:|||||.|:|:||..||..||...  ..|.:|.||..
 Worm   403 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVS 465

  Fly   257 CDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAP---- 317
            ...|.||:|:::|:.|:::|:|||.:||.||..:|.:|:|:|.||...||..|..:::|.|
 Worm   466 GKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSK 530

  Fly   318 ----------YQPTISGAEDLSNFENFEFKDRYKSRINRHP---ELFANF 354
                      ..|.:.|..|..:|.. |.::..:..|...|   |||..|
 Worm   531 GESNGRLFEALYPRVDGPADTRHFVE-EVQEPTEFVIAATPQLEELFVEF 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	146/304 (48%)
kin-1	NP_001368699.1	STKc_PKA	254..556	CDD:271111	146/303 (48%)