Protein Alignment Pka-C2 and rps6kal

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_956367.1
• Gene: rps6kal / 337670
• ZFINID: ZDB-GENE-030131-9616
• Length: 740
• Species: Danio rerio
• Alignment Length: 364
• Identity: 118/364 - (32%)
• Similarity: 187/364 - (51%)
• Gaps: 51/364 - (14%)

  Fly    28 EERWNHQTQSPYTNL---------------ENYITRAVLGNGSFGTVMLVREKSGKN---YYAAK 74
            ||.:.|..:..|..:               ..:....|||.||||.|.|||:..|.:   .||.|
Zfish    35 EESYTHCDEGAYKEIPITHHVKEGCEKADPSQFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMK 99

  Fly    75 MMSK-----EDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYH 134
            ::.|     .|.||.|.      |:.:|.....||::.|..:.:....|||||..:.||::|:..
Zfish   100 VLKKASLKVRDRVRTKM------ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRL 158

  Fly   135 RRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKR---VDGR 196
            .:...|.|:..:||.|::||||:::|.:.::||||||||||||:.|:||:||||.:|.   .|.:
Zfish   159 SKEVMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQDKK 223

  Fly   197 TSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKM 261
            ..:.|||.||:|||:|..|.:.:|.|||:.|:|::|.:.|..||...:|:..:  :.|......|
Zfish   224 AYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDRNETM--NMILKAKLGM 286

  Fly   262 PSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAE 326
            |.:.:.:.:.|:..|.:.:.|.|||...||..::|.|.:|..:||..:..:|:..|::|. ||..
Zfish   287 PQFLSLEAQGLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPA-SGKP 350

  Fly   327 DLSNFENFEFKDRYKSR-----------INRHPELFANF 354
            |    :.|.|...:.::           .|.| :||..|
Zfish   351 D----DTFCFDPEFTAKTPKDSPGIPPSANAH-QLFKGF 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	107/301 (36%)
rps6kal	NP_956367.1	STKc_RSK_N	71..387	CDD:270734	114/328 (35%)
		STKc_RSK4_C	415..709	CDD:271079