DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C2 and Pkg21D

DIOPT Version :9

Sequence 1:	NP_733397.2	Gene:	Pka-C2 / 43644	FlyBaseID:	FBgn0000274	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	112/322 - (34%)
Similarity:	179/322 - (55%)	Gaps:	14/322 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QTQSPYTNLENYITRAVLGNGSFGTVMLVR--EKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHV 96
            |.:.|...|.:....:.||.|.||.|.||:  .:...:.:|.|.:.|..:|..||..|:.:|:|:
  Fly   446 QQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHI 510

  Fly    97 LNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHK 161
            :.::|.||:..|..:.:...|:|::|....|||:::..|....|.:..|:|....|..|.||:|.
  Fly   511 MLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHA 575

  Fly   162 MHLMYRDLKPENILLDQRGYIKITDFGFTKRV--DGRTSTLCGTPEYLAPEIVQLRPYNKSVDWW 224
            ..::||||||||::||:|||:||.||||.|::  ..:|.|.||||||:||||:..:.::::||:|
  Fly   576 RGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYW 640

  Fly   225 AFGILVYEFVAGRSPFAIHNRDVILMYSKIC--ICDYKMPSYFTSQLRSLVESLMQVDTSKRLGN 287
            |.|||::|.:.|..||:.  .|.:..|:.|.  |.....|.:.:.....|::.|.:...|:|||.
  Fly   641 ALGILIHELLNGTPPFSA--PDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGY 703

  Fly   288 SNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFEFKDRYKSRINRHPE 349
            ...|..|:|.|.||.|.||.|:.:|.:..|:...|:...|:..|      ||:...:|..|:
  Fly   704 QTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYF------DRFPCDLNEPPD 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	105/296 (35%)
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736
		CAP_ED	185..285	CDD:237999
		CAP_ED	304..419	CDD:237999
		Pkinase	457..717	CDD:278497	94/261 (36%)
		STKc_cGK	463..724	CDD:270724	99/262 (38%)
		S_TK_X	719..>760	CDD:214529	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440849
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940