Protein Alignment Pka-C2 and Sgk2

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_038759.1
• Gene: Sgk2 / 27219
• MGIID: 1351318
• Length: 367
• Species: Mus musculus
• Alignment Length: 308
• Identity: 120/308 - (38%)
• Similarity: 188/308 - (61%)
• Gaps: 7/308 - (2%)

  Fly    50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHV-LNAARFPFLIYLVDSTK 113
            |:|.|::|.|:|.:.||...:||.|::.|:.:::.|:..|:..|::| |...|.|||:.|..|.:
Mouse    40 VIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQ 104

  Fly   114 CFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQ 178
            ..:.||.:|..|||||||.:.:|.|:|.|..||||.|:||.|:.|:|.::::||||||||||||.
Mouse   105 TPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDC 169

  Fly   179 RGYIKITDFGFTKRV---DGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPF 240
            :|::.:||||..|..   :..|||.||||||||||:::..||:::||||..|.::||.:.|..||
Mouse   170 QGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPF 234

  Fly   241 AIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVD 305
              .|.||..||..|.....::|...|.....|::.|:..|..:|||:..| ..|:|:|.:|..::
Mouse   235 --FNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKED-FLDIKNHMFFSPIN 296

  Fly   306 WFGILNQEVTAPYQPTISGAEDLSNFENFEFKDRYKSRINRHPELFAN 353
            |..:.::.:|.|:.|.:.|..||.:|:....::.....|...|:..|:
Mouse   297 WDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTVAS 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	117/287 (41%)
Sgk2	NP_038759.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Protein Kinases, catalytic domain	39..359	CDD:473864	120/308 (39%)
		Nuclear localization signal. /evidence=ECO:0000250	68..78		2/9 (22%)