Protein Alignment Pka-C2 and Akt2

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_008757330.1
• Gene: Akt2 / 25233
• RGDID: 2082
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 305
• Identity: 118/305 - (38%)
• Similarity: 180/305 - (59%)
• Gaps: 15/305 - (4%)

  Fly    50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKC 114
            :||.|:||.|:|||||:...|||.|::.||.::...:|||...|..||...|.|||..|..:.:.
  Rat   172 LLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQT 236

  Fly   115 FDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQR 179
            .|.|..::...||||||.:..|.|.|.|..||||.|::..||||:|...::|||:|.||::||:.
  Rat   237 HDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKD 301

  Fly   180 GYIKITDFGFTKR--VDGRT-STLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFA 241
            |:|||||||..|.  .||.| .|.||||||||||:::...|.::||||..|:::||.:.||.||
  Rat   302 GHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF- 365

  Fly   242 IHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDW 306
             :|:|...::..|.:.:.:.|.....:.:||:..|::.|..:|||.....:.:|..|.:|..::|
  Rat   366 -YNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 429

  Fly   307 FGILNQEVTAPYQPTISGAEDLSNFENFEF---------KDRYKS 342
            ..::.:::..|::|.::...|...|:: ||         .|||.|
  Rat   430 QDVVQKKLLPPFKPQVTSEVDTRYFDD-EFTAQSITITPPDRYDS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	112/286 (39%)
Akt2	XP_008757330.1	PH_PKB	32..126	CDD:269947
		STKc_PKB_beta	171..493	CDD:173686	118/305 (39%)