Protein Alignment Pka-C2 and Prkaca

DIOPT Version :9

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_032880.1
• Gene: Prkaca / 18747
• MGIID: 97592
• Length: 351
• Species: Mus musculus
• Alignment Length: 335
• Identity: 157/335 - (46%)
• Similarity: 220/335 - (65%)
• Gaps: 4/335 - (1%)

  Fly    11 NSKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKM 75
            :.:|.....|.....:|.::|...:|:. ..|:.:.....||.||||.||||:.|...|:||.|:
Mouse    11 SEQESVKEFLAKAKEDFLKKWETPSQNT-AQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKI 74

  Fly    76 MSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKF 140
            :.|:.:|:|||:.|..|||.:|.|..||||:.|..|.|....||:::..|.|||:||:.||:.:|
Mouse    75 LDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRF 139

  Fly   141 NEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPE 205
            :|.||||||||:.|..||:|.:.|:||||||||:|:||:|||::|||||.|||.|||.|||||||
Mouse   140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPE 204

  Fly   206 YLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLR 270
            ||||||:..:.|||:|||||.|:|:||..||..||...  ..|.:|.||.....:.||:|:|.|:
Mouse   205 YLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLK 267

  Fly   271 SLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFE 335
            .|:.:|:|||.:||.||..:|.:|:|:|.||...||..|..::|.||:.|...|..|.|||:::|
Mouse   268 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYE 332

  Fly   336 FKDRYKSRIN 345
             ::..:..||
Mouse   333 -EEEIRVSIN 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	148/290 (51%)
Prkaca	NP_032880.1	STKc_PKA	42..331	CDD:271111	148/290 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833010
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S234
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.760