Protein Alignment Pka-C2 and egl-4

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001294450.1
• Gene: egl-4 / 176991
• WormBaseID: WBGene00001173
• Length: 783
• Species: Caenorhabditis elegans
• Alignment Length: 322
• Identity: 109/322 - (33%)
• Similarity: 182/322 - (56%)
• Gaps: 18/322 - (5%)

  Fly    19 ILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGK-NYYAAKMMSKEDLV 82
            |:|:...||.:          ..|:|....|.||.|.||.|.||.....| ..:|.|.:.|:.:|
 Worm   456 IVDDFREEFAQ----------VTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIV 510

  Fly    83 RLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARF 147
            ..:|..|:..|::::......:::.|..:.:...::|::|.:..||||::..|....|::..|||
 Worm   511 DTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARF 575

  Fly   148 YAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRV-DGR-TSTLCGTPEYLAPE 210
            |.|.|...|||:|:.:::||||||||.||...||:|:.||||.|:: .|| |.|.||||||::||
 Worm   576 YVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPE 640

  Fly   211 IVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKIC--ICDYKMPS-YFTSQLRSL 272
            |:..:.::::.|:||.||.:.|.:.||.||  ...|.:..|:.|.  :...::|: .......:|
 Worm   641 IILNKGHDQAADYWALGIYICELMLGRPPF--QASDPMKTYTLILKGVDALEIPNRRIGKTATAL 703

  Fly   273 VESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENF 334
            |:.|.:.:..:|||:.:.|.:|::.|.||.|.||.|:.::.:..|..|.:|...|::||:|:
 Worm   704 VKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNY 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	103/296 (35%)
egl-4	NP_001294450.1	CAP_ED	201..314	CDD:237999
		CAP_ED	319..437	CDD:237999
		STKc_cGK	478..739	CDD:270724	94/262 (36%)
		S_TK_X	734..783	CDD:214529	11/32 (34%)