Protein Alignment Pka-C2 and prkg2

DIOPT Version :10

• Sequence 1: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_002934043.3
• Gene: prkg2 / 100497736
• XenbaseID: XB-GENE-951552
• Length: 787
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 125/356 - (35%)
• Similarity: 196/356 - (55%)
• Gaps: 31/356 - (8%)

  Fly     5 TSQYVFNSKEDY--NVILDNMSREFEERWNHQ--------------------TQSPYTNLENYIT 47
            |.:.:....|.|  |:.||:..|..:...|.:                    :.||:.|||...|
 Frog   419 TYEELMKCLEGYVANLTLDDERRHAKSPVNERHLRAVSMELNKMKQTLARFPSASPFENLEIVTT 483

  Fly    48 RAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDST 112
               ||.|.||.|.||:.|:....:|.|.:.|..:|..:|..|:|:||::|..|..||::.|..:.
 Frog   484 ---LGVGGFGRVELVKVKNENLVFALKCIKKRHIVDNRQQEHIHSEKNILEEACSPFIVKLYCTF 545

  Fly   113 KCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLD 177
            |...|:|::|....||||:|..|....|:|..|:|....|..|.||:|:..::||||||||:|||
 Frog   546 KDNKYVYMLLEACLGGELWSILRDRGSFDEPTAKFCTGCVTEAFEYLHQKGVLYRDLKPENLLLD 610

  Fly   178 QRGYIKITDFGFTKRV--DGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPF 240
            ..||:|:.||||.|::  ..:|.|.||||||:|||::..:.::.|||:|:.|||:||.:.|..||
 Frog   611 SEGYVKLVDFGFAKKIFPGQKTWTFCGTPEYVAPEVILNKGHSFSVDFWSLGILLYELLTGSPPF 675

  Fly   241 AIHNRDVILMYSKICICDYKMPSY--FTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQG 303
            .  ..|.:::|:.|.....|:..|  .|.:...|:..|.:.:.::||||..:|.:|:|.|.||.|
 Frog   676 T--GPDQMIIYNLILQGIEKIEFYKNITKRPEDLIRRLCRENPAERLGNMKNGIADIKKHRWFNG 738

  Fly   304 VDWFGILNQEVTAPYQPTISGAEDLSNFENF 334
            .:|.|:..:.:.:|.:|.:.|..|.|.|:::
 Frog   739 FNWEGLNTRSLPSPLKPELEGPTDHSYFDSY 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	113/294 (38%)
prkg2	XP_002934043.3	CAP_ED	194..303	CDD:237999
		CAP_ED	312..427	CDD:237999	1/7 (14%)
		STKc_cGK	484..743	CDD:270724	104/260 (40%)