Protein Alignment CG12069 and TPK2

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_015121.1
• Gene: TPK2 / 855898
• SGDID: S000006124
• Length: 380
• Species: Saccharomyces cerevisiae
• Alignment Length: 324
• Identity: 143/324 - (44%)
• Similarity: 208/324 - (64%)
• Gaps: 21/324 - (6%)

  Fly    44 LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTV 108
            |.|::|..|||:||||:|.|||...:|.|||.|.|.|.|:||.|||.|...|:.:|:.:..|..:
Yeast    67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLI 131

  Fly   109 NLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKP 173
            .:..:::|..::::|:..|.|||||:..||.::|....|:||||:|.|||||||..:::||||||
Yeast   132 RMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKP 196

  Fly   174 ENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAG 238
            |||::|:||::|:|||||||:|:|.|.||||||:|:.||:|.:|||..|||||:.|||::|.:||
Yeast   197 ENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAG 261

  Fly   239 HSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF 303
            ::||  ::...|..|.||.:.....|.||...:..|:..|:..||::|.|||.:|:||||.|.||
Yeast   262 YTPF--YDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWF 324

  Fly   304 KDVEWIPLLNQTVNAPYVPNISN-----------PEDISNFDKVSDKPRPKAKTMRHEEAFADF 356
            .:|.|..||.:.:..||.|.|::           ||:..::....|.|        :.|.|.||
Yeast   325 SEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDP--------YAEYFQDF 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	136/300 (45%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	134/290 (46%)