Protein Alignment CG12069 and YPK1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_012796.1
• Gene: YPK1 / 853733
• SGDID: S000001609
• Length: 680
• Species: Saccharomyces cerevisiae
• Alignment Length: 324
• Identity: 123/324 - (37%)
• Similarity: 184/324 - (56%)
• Gaps: 10/324 - (3%)

  Fly    22 LDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKT 86
            |.|:....:.|.:.|.|   ..:||:::...:|.||||||..||::::...||.|.:.|..||..
Yeast   325 LGKINISIDYKPSRNKP---LSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSK 386

  Fly    87 KQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYA 151
            .:|:|.::|:.||..:..|..|.|..|::..:.||.||..|.|||||.:.:|..:|...:||||.
Yeast   387 SEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYT 451

  Fly   152 AQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAK---KVETRTMTLCGTPEYLPPEI 213
            |::..||:.||...::|||||||||::|..|::.:.|||..|   |.:.:|.|.|||||||.||:
Yeast   452 AELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPEL 516

  Fly   214 IQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHL 278
            :....|..:||||..|||::|.:.|..|:  ::.||..||.||.:.....|..|....:.|:..|
Yeast   517 LLGLGYTKAVDWWTLGVLLYEMLTGLPPY--YDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGL 579

  Fly   279 LQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDKVSDKPRP 342
            |..|.::|.|  .||..:|:.|.:|..:.|..||.:....||.|.:||..|.||||:...:.:|
Yeast   580 LSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKP 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	116/292 (40%)
YPK1	NP_012796.1	YPK1_N_like	116..342	CDD:212165	5/19 (26%)
		Protein Kinases, catalytic domain	352..663	CDD:473864	116/294 (39%)