Protein Alignment CG12069 and YPK3

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_009584.1
• Gene: YPK3 / 852316
• SGDID: S000000232
• Length: 525
• Species: Saccharomyces cerevisiae
• Alignment Length: 412
• Identity: 121/412 - (29%)
• Similarity: 193/412 - (46%)
• Gaps: 92/412 - (22%)

  Fly    23 DKLREDFNKKFATNTPSP-----------STGLDDYEIKATLGSGSFGKVQLVRERESGVYYASK 76
            |.:|.:.|:  .:.||..           |..|.|::....||.|::|||.||::..:...||.|
Yeast    95 DAMRTNTNR--LSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMK 157

  Fly    77 QLSKDQIV--------------------------KTKQVSHVMSEKNVLRSMTFPNTVNLIASYK 115
            ||.|.:|:                          .:|::....:|:::|..:..||.|.|..|:.
Yeast   158 QLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFH 222

  Fly   116 DFDSLYLVLPLIGGGELFTYHRKVR-KFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMD 179
            |...|||:|..|.||||| ||.|.. ...|....||||::..||.:||...::||||||||.:::
Yeast   223 DNSKLYLLLQYIPGGELF-YHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLN 286

  Fly   180 KNGYLKVTDFGFAKKVETRT-------------MTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVL 231
            :.|:|.:||||.:||....:             .::.|||||..|||:..|.|..:.||::.|.|
Yeast   287 QRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCL 351

  Fly   232 VFEFVAGHSPFSAHNRDVMSMYNKICEADY--KMPSYFSGALRHLVDHLLQVDLSKRFGNLIN-- 292
            :::.:.|..|::..|..|  :.|||.:...  |:|.|.|..::.:::.||:.:.:||: |:..
Yeast   352 LYDMLVGKPPYTGSNHKV--IINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRW-NVDKYW 413

  Fly   293 -----GNRDIK---------------EHEWFKDVEWIPL----LNQTVNAPYVPNISNPEDISNF 333
                 .|:..|               ||..|:.::|..|    |.:|...|.||.|::.|...||
Yeast   414 AKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENF 478

  Fly   334 DKVSDKPRPKAKTMRHEEAFAD 355
            |       .:..:|.:||.:.|
Yeast   479 D-------TEFTSMSYEETYTD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	109/357 (31%)
YPK3	NP_009584.1	STKc_AGC	134..406	CDD:270693	89/274 (32%)
		S_TK_X	445..516	CDD:214529	16/56 (29%)