Protein Alignment CG12069 and Rps6ka6

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_080225.2
• Gene: Rps6ka6 / 67071
• MGIID: 1914321
• Length: 860
• Species: Mus musculus
• Alignment Length: 342
• Identity: 116/342 - (33%)
• Similarity: 185/342 - (54%)
• Gaps: 36/342 - (10%)

  Fly    16 VDYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRER---ESGVYYASKQ 77
            |..|.|...::|.:.|      ..|:    .:::...||.||||||.|||::   ::|..||.|.
Mouse   168 VKEIPITQHVKEGYEK------ADPA----QFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKV 222

  Fly    78 LSKDQI-----VKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHR 137
            |.|..:     |:||.      |:::|..:..|..|.|..:::....|||:|..:.||::||...
Mouse   223 LRKASLKVRDRVRTKM------ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLS 281

  Fly   138 KVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKK---VETRT 199
            |...|||:..:||.|::.|||::||...::|||||||||::|:.|::|:||||.:|:   .|.:.
Mouse   282 KEVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKA 346

  Fly   200 MTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMP 264
            .:.|||.||:.||::..:.:..|.|||::|||:||.:.|..||...:|:  ...|.|.:|...||
Mouse   347 YSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRN--ETMNMILKAKLGMP 409

  Fly   265 SYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPED 329
            .:.|...:.|:..|.:.:.:.|.|:  .|..::|.|.:|..::|..|..:.|..|:.|....|:|
Mouse   410 QFLSAEAQSLLRMLFKRNPANRLGS--EGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDD 472

  Fly   330 ISNFDKVSDKPRPKAKT 346
            ...||     |...|||
Mouse   473 TFCFD-----PEFTAKT 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	105/300 (35%)
Rps6ka6	NP_080225.2	STKc_RSK_N	193..507	CDD:270734	110/307 (36%)
		STKc_RSK_C	542..828	CDD:270993