Protein Alignment CG12069 and PRKCH

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_047287541.1
• Gene: PRKCH / 5583
• HGNCID: 9403
• Length: 782
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 114/305 - (37%)
• Similarity: 175/305 - (57%)
• Gaps: 7/305 - (2%)

  Fly    43 GLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLR-SMTFPN 106
            |:|::|....||.||||||.|.|.:|:|..||.|.|.||.|::...|...|:||.:|. :...|.
Human   450 GIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPF 514

  Fly   107 TVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDL 171
            ...|...::..|.|:.|:..:.||:|..:.:|.|:|.|.:||||||::..||.:||...::||||
Human   515 LTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL 579

  Fly   172 KPENIMMDKNGYLKVTDFGFAKK---VETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVF 233
            |.:|:::|..|:.|:.|||..|:   ....|.|.||||:|:.|||:|...||.:|||||.|||::
Human   580 KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLY 644

  Fly   234 EFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRD-I 297
            |.:.||:||.|.|.|  .::..|...:...|::.......::...:..:.:.|.|:|..|... |
Human   645 EMLCGHAPFEAENED--DLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAI 707

  Fly   298 KEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDKVSDKPRP 342
            ..|.:||:::|..|.::.:..|:.|.|.:.||:||||....|..|
Human   708 LRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEP 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	110/294 (37%)
PRKCH	XP_047287541.1	C2_PKC_epsilon	8..122	CDD:175981
		C1_nPKC_epsilon-like_rpt1	265..325	CDD:410385
		C1_nPKC_epsilon-like_rpt2	343..397	CDD:410388
		STKc_nPKC_eta	458..780	CDD:270742	111/297 (37%)