Protein Alignment CG12069 and PRKCD

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001341605.1
• Gene: PRKCD / 5580
• HGNCID: 9399
• Length: 695
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 112/329 - (34%)
• Similarity: 181/329 - (55%)
• Gaps: 17/329 - (5%)

  Fly    39 SPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLR-SM 102
            |....::::.....||.||||||.|...:..|.|:|.|.|.||.::....|...|.||.||. :.
Human   360 SSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAA 424

  Fly   103 TFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLL 167
            ..|...:||.:::..|.|:.|:..:.||:|..:.:...:|...:|.||||::...|::||...::
Human   425 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGII 489

  Fly   168 YRDLKPENIMMDKNGYLKVTDFGFAKK---VETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFG 229
            |||||.:|:::|::|::|:.|||..|:   .|:|..|.||||:|:.|||:|...|..|||||:||
Human   490 YRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFG 554

  Fly   230 VLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGN 294
            ||::|.:.|.|||  |..|...::..|.......|.:.:...:.:::.|.:.:.:||.|  :.||
Human   555 VLLYEMLIGQSPF--HGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLG--VTGN 615

  Fly   295 RDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDK--VSDKPRPKAKTMR-----HEEA 352
              ||.|.:||.:.|..|..:.:..|:.|.:.:|.|.||||:  :::|.|.......     .:.|
Human   616 --IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSA 678

  Fly   353 FADF 356
            ||.|
Human   679 FAGF 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	104/293 (35%)
PRKCD	NP_001341605.1	C1_nPKC_theta-like_rpt1	171..231	CDD:410384
		C1_nPKC_theta-like_rpt2	250..299	CDD:410387
		STKc_nPKC_delta	372..687	CDD:173710	111/317 (35%)