Protein Alignment CG12069 and PRKACB

DIOPT Version :9

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_891993.1
• Gene: PRKACB / 5567
• HGNCID: 9381
• Length: 398
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 165/359 - (45%)
• Similarity: 235/359 - (65%)
• Gaps: 14/359 - (3%)

  Fly     6 EQAQMHFSPKVDYILILD--------KLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQ 62
            |...:|||   ::..:.|        |.:|||.||:...|.: :.||:|:|.|.|||:||||:|.
Human    46 ENDSLHFS---EHTALWDRSMKEFLAKAKEDFLKKWENPTQN-NAGLEDFERKKTLGTGSFGRVM 106

  Fly    63 LVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLI 127
            ||:.:.:..|||.|.|.|.::||.||:.|.::||.:|:::.||..|.|..::||..:||:|:..:
Human   107 LVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYV 171

  Fly   128 GGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFA 192
            .|||:|::.|::.:|:|..|||||||:.|..||||...|:||||||||:::|..||::|||||||
Human   172 PGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 236

  Fly   193 KKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKIC 257
            |:|:.||.|||||||||.||||.||.|..:|||||.|||::|..||:.||.|.  ..:.:|.||.
Human   237 KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIV 299

  Fly   258 EADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVP 322
            ....:.||:||..|:.|:.:||||||:||||||.||..|||.|:||...:||.:..:.|.||::|
Human   300 SGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 364

  Fly   323 NISNPEDISNFDKVSDKPRPKAKTMRHEEAFADF 356
            ......|.||||...::....:.|.:..:.|.:|
Human   365 KFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	PTZ00263	44..356	CDD:140289	151/311 (49%)
		PKc_like	45..335	CDD:304357	147/289 (51%)
PRKACB	NP_891993.1	STKc_PKA	89..378	CDD:271111	148/290 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.810