Protein Alignment CG12069 and aurka

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001016570.1
• Gene: aurka / 549324
• XenbaseID: XB-GENE-853082
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 315
• Identity: 109/315 - (34%)
• Similarity: 159/315 - (50%)
• Gaps: 26/315 - (8%)

  Fly     2 GPQ----PEQAQMHFSPKV------DYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSG 56
            ||.    |:|.....:|.|      |....|...:|:..||        ...|:|:||...||.|
 Frog    99 GPNENRTPQQTSHSSTPNVEKKGSTDQGKTLAVPKEEGKKK--------QWCLEDFEIGRPLGKG 155

  Fly    57 SFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLY 121
            .||.|.|.|||||....|.|.|.|.|:.|......:..|..:...:..||.:.|...:.|...:|
 Frog   156 KFGNVYLARERESKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDAARVY 220

  Fly   122 LVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKV 186
            |:|....|||||...:||.:|.|:::..|..|:..||.|.|..::::||:||||:::..||.||:
 Frog   221 LILDYAPGGELFRELQKVTRFDEQKSALYIKQLAEALLYCHSKNVIHRDIKPENLLLGANGELKI 285

  Fly   187 TDFGFAKKV-ETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVM 250
            .|||::... .:|..|||||.:|||||:|:.:.:...||.|:.|||.:||:.|..||.....  .
 Frog   286 ADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFETDTH--Q 348

  Fly   251 SMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKD 305
            ..|.:|.:.:::.|||.|...|.||..||:.:.:.|..  :.|   :.||.|..|
 Frog   349 ETYRRISKVEFQYPSYVSEGARDLVSKLLKHNPNHRLS--LKG---VLEHPWIID 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	97/262 (37%)
aurka	NP_001016570.1	STKc_Aurora-A	140..397	CDD:271018	97/263 (37%)