DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12069 and prkaca

DIOPT Version :9

Sequence 1:	NP_651819.1	Gene:	CG12069 / 43643	FlyBaseID:	FBgn0039796	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_012808518.1	Gene:	prkaca / 549157	XenbaseID:	XB-GENE-5954970	Length:	383	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	162/336 - (48%)
Similarity:	230/336 - (68%)	Gaps:	5/336 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LDKLREDFNKKFATNTPSPSTG-LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVK 85
            |.|.:|||.||:  ..|:.:|. |:.:|...|||:||||:|.|||.:|:|.::|.|.|.|.::||
Frog    52 LAKAKEDFLKKW--ENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVK 114

  Fly    86 TKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFY 150
            .||:.|.::||.:|:::.||..|.|..|:||..:||:|:..:.|||:|::.|::.:|:|..||||
Frog   115 LKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFY 179

  Fly   151 AAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQ 215
            |:|:.|..||||...|:||||||||:::|:.||::||||||||:|:.||.|||||||||.||||.
Frog   180 ASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIIL 244

  Fly   216 SKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQ 280
            ||.|..:|||||.|||::|..||:.||.|.  ..:.:|.||.....:.||:||..|:.|:.:|||
Frog   245 SKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 307

  Fly   281 VDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDKVSDKPRPKAK 345
            |||:||||||.||..|||.|:||...:||.:..:.|.||::|....|.|.||||...::....:.
Frog   308 VDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSI 372

  Fly   346 TMRHEEAFADF 356
            |.:..:.|:||
Frog   373 TEKCAKEFSDF 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	PTZ00263	44..356	CDD:140289	151/311 (49%)
CG12069	NP_651819.1	PKc_like	45..335	CDD:304357	147/289 (51%)
prkaca	XP_012808518.1	STKc_PKA	74..363	CDD:271111	148/290 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020