Protein Alignment CG12069 and aPKC

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 103/310 - (33%)
• Similarity: 174/310 - (56%)
• Gaps: 16/310 - (5%)

  Fly    40 PST----GLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLR 100
            |.|    .|:|:|:...:|.||:.||.:|..|.:...||.|.:.|..:...:.:..|.:||:|..
  Fly   605 PGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFE 669

  Fly   101 SMT-FPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHC 164
            :.: .|..|.|.:.::....|:.|:..:.||:|..:.::.|:..|:.||||||::.|||.:||..
  Fly   670 TASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEK 734

  Fly   165 SLLYRDLKPENIMMDKNGYLKVTDFGFAK---KVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWW 226
            .::|||||.:|:::|..|::|:||:|..|   :....|.|.||||.|:.|||::.:.||.|||||
  Fly   735 GIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWW 799

  Fly   227 AFGVLVFEFVAGHSPF----SAHNRDVMS---MYNKICEADYKMPSYFSGALRHLVDHLLQVDLS 284
            |.|||::|.:||.|||    ::.|.|..:   ::..|.|...::|...|.....::...|..:.:
  Fly   800 ALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPA 864

  Fly   285 KRFG-NLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNF 333
            .|.| :..:...||..|.:||:::|..|..:.|..|:.|.:.:..|::||
  Fly   865 DRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANF 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	100/301 (33%)
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	98/295 (33%)