Protein Alignment CG12069 and kin-1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001368699.1
• Gene: kin-1 / 3565407
• WormBaseID: WBGene00002189
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 354
• Identity: 168/354 - (47%)
• Similarity: 230/354 - (64%)
• Gaps: 25/354 - (7%)

  Fly    22 LDKLREDFNKKFATNTPSPSTG-LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVK 85
            |||.||||.:::  ..|:.:|. |||::...|||:||||:|.||:.::||.|||.|.|.|.::||
 Worm   232 LDKAREDFKQRW--ENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVK 294

  Fly    86 TKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFY 150
            .|||.|.::||.:|:::.||..||:..|:||..:||:||..|.|||:|::.|::.:|:|..:|||
 Worm   295 LKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFY 359

  Fly   151 AAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQ 215
            |||:.||.||||...|:||||||||:::|..||||:|||||||:|:.||.|||||||||.||||.
 Worm   360 AAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIIL 424

  Fly   216 SKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQ 280
            ||.|..:|||||.|||::|..||:.||.|.  ..:.:|.||.....|.||:||..|:.|:.:|||
 Worm   425 SKGYNKAVDWWALGVLIYEMAAGYPPFFAD--QPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQ 487

  Fly   281 VDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAP--------------YVPNISNPEDIS 331
            |||:||:|||.||..|||.|:||...:||.:..:.:..|              ..|.:..|.|..
 Worm   488 VDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGPADTR 552

  Fly   332 NFDKVSDKPRPK----AKTMRHEEAFADF 356
            :|  |.:...|.    |.|.:.||.|.:|
 Worm   553 HF--VEEVQEPTEFVIAATPQLEELFVEF 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	150/303 (50%)
kin-1	NP_001368699.1	STKc_PKA	254..556	CDD:271111	150/305 (49%)