DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12069 and CG4839

DIOPT Version :9

Sequence 1:	NP_651819.1	Gene:	CG12069 / 43643	FlyBaseID:	FBgn0039796	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	125/359 - (34%)
Similarity:	191/359 - (53%)	Gaps:	47/359 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VDYILILDKLRE-DFNKKFATNTPSPSTGLD---DY------EIK--ATLGSGSFGKVQLVRERE 68
            :.|:..:.:||| ..:::..|:..|.:..|:   :|      |:|  ||||.|:||:|.||...:
  Fly   651 ISYLGTIKQLREKPSSQRNDTSGRSSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAYNQ 715

  Fly    69 SGVYYASKQLSKDQIVKTKQVSHVMSEKNV-LRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGEL 132
            ..:  |.|.:.|.::||..|:.||.:|||| ::....|..|.|..:|::...:|.::....||::
  Fly   716 QAL--ALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDV 778

  Fly   133 FTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV-- 195
            :|...|.:.|.||.|:|.|..|..|.:|||....:||||||||:|:..:||.|:.||||||.|
  Fly   779 WTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQ 843

  Fly   196 ETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEA- 259
            ..:|.|..|||||:.||||..:.:..:||:||.|:||:|.:.|.:||...|:  :.:|.:|...
  Fly   844 NEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQ--IKIYQQILSGI 906

  Fly   260 -DYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEW-------------IP 310
             ...|||....:.:|||.||.:...::|.|....|..|||.|.||:.::|             .|
  Fly   907 DVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRP 971

  Fly   311 LLNQT---------VNAPYVPNISNPEDISNFDK 335
            |.:.|         |...|.|    ||::|.:||
  Fly   972 LKSWTDLQYFGPSGVENDYEP----PEELSGWDK 1001

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	PTZ00263	44..356	CDD:140289	119/330 (36%)
CG12069	NP_651819.1	PKc_like	45..335	CDD:304357	116/327 (35%)
CG4839	NP_609349.1	Crp	428..577	CDD:223736
		CAP_ED	431..539	CDD:237999
		Crp	544..>650	CDD:223736
		CAP_ED	550..663	CDD:237999	3/11 (27%)
		S_TKc	695..951	CDD:214567	102/259 (39%)
		STKc_cGK	700..957	CDD:270724	101/260 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010