Protein Alignment CG12069 and Rps6ka6

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001178650.1
• Gene: Rps6ka6 / 317203
• RGDID: 1560817
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 116/337 - (34%)
• Similarity: 183/337 - (54%)
• Gaps: 32/337 - (9%)

  Fly    26 REDFNKKFATNTPSPSTGLD-----DYEIKATLGSGSFGKVQLVRER---ESGVYYASKQLSKDQ 82
            |||..|:... |.....|.:     .:::...||.||||||.|||::   ::|..||.|.|.|..
  Rat   165 REDLVKEIPI-TQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKAS 228

  Fly    83 I-----VKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKF 142
            :     |:||.      |:::|..:..|..|.|..:::....|||:|..:.||::||...|...|
  Rat   229 LKVRDRVRTKM------ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLF 287

  Fly   143 TEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKK---VETRTMTLCG 204
            ||:..:||.|::.|||::||...::|||||||||::|:.|::|:||||.:|:   .|.:..:.||
  Rat   288 TEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCG 352

  Fly   205 TPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSG 269
            |.||:.||::..:.:..|.|||::|||:||.:.|..||...:|:  ...|.|.:|...||.:.|.
  Rat   353 TVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRN--ETMNMILKAKLGMPQFLSA 415

  Fly   270 ALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFD 334
            ..:.|:..|.:.:.:.|.|:  .|..::|.|.:|..::|..|..:.|..|:.|....|:|...||
  Rat   416 EAQSLLRMLFKRNPANRLGS--EGVEEVKRHAFFSSIDWNKLYKREVQPPFRPASGKPDDTFCFD 478

  Fly   335 KVSDKPRPKAKT 346
                 |...|||
  Rat   479 -----PEFTAKT 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	105/305 (34%)
Rps6ka6	NP_001178650.1	STKc_RSK_N	194..508	CDD:270734	110/307 (36%)
		STKc_RSK_C	543..829	CDD:270993