Protein Alignment CG12069 and pka1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_595159.1
• Gene: pka1 / 2539781
• PomBaseID: SPBC106.10
• Length: 512
• Species: Schizosaccharomyces pombe
• Alignment Length: 326
• Identity: 146/326 - (44%)
• Similarity: 203/326 - (62%)
• Gaps: 6/326 - (1%)

  Fly    15 KVDYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLS 79
            ||....:||..|.....  |.:|.....|:.|:....|||:||||:|.||:...:.:|||.|.|.
pombe   171 KVRVSQLLDLQRRRIRP--ADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLE 233

  Fly    80 KDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTE 144
            |.:||..||:.|...|:.:|..:..|....|..:::|..:|::|:....|||||:..||..:|.|
pombe   234 KKKIVDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPE 298

  Fly   145 KQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET-RTMTLCGTPEY 208
            |.|:||||:|.|||:||||..::||||||||:::|:.|:||:.||||||:|.| ...||||||:|
pombe   299 KVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDY 363

  Fly   209 LPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRH 273
            |.||||..|||..:.|||:.|:|:||.:||:.||.:.|  .|.:|..|.|.....|||||.|...
pombe   364 LAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSEN--PMKLYENILEGKVNYPSYFSPASID 426

  Fly   274 LVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNI-SNPEDISNFDKVS 337
            |:.||||.|::.|:|||.:|:.||..|.||:|:.|..:|.:.:..||||.| :...|.|.||..:
pombe   427 LLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAYA 491

  Fly   338 D 338
            |
pombe   492 D 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	136/291 (47%)
pka1	NP_595159.1	STKc_PKA_like	199..490	CDD:270732	137/292 (47%)