Protein Alignment CG12069 and akt-1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001023646.1
• Gene: akt-1 / 179424
• WormBaseID: WBGene00000102
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 374
• Identity: 124/374 - (33%)
• Similarity: 192/374 - (51%)
• Gaps: 56/374 - (14%)

  Fly     3 PQPEQAQMHFSPKVDYILILDKLREDFNKKFATNTPS----PSTG-------------------- 43
            ||.|..:.:..||:|         ||  .:||....:    ||:|
 Worm   127 PQEELMETNQQPKID---------ED--SEFAGAAHAIMGQPSSGHGDNCSIDFRASMISIADTS 180

  Fly    44 ---------LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVL 99
                     ::|::....||.|:||||.|.:|:.:...||.|.|.||.|:..::|:|.::|..||
 Worm   181 EAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVL 245

  Fly   100 RSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYH--RKVRK----FTEKQARFYAAQVFLAL 158
            :....|....|..|::..|.|..|:....||:|: ||  |:|:.    |:|.:||||.:::.|||
 Worm   246 QRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLY-YHLNREVQMNKEGFSEPRARFYGSEIVLAL 309

  Fly   159 EYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKK---VETRTMTLCGTPEYLPPEIIQSKPYG 220
            .|||..|::|||||.||:::||:|::|:.|||..|:   ...:|.|.|||||||.||::....||
 Worm   310 GYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYG 374

  Fly   221 TSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSK 285
            ..||||..||:::|.:.|..||  :::|...::..|...|.:.||..|...|.|:..||..|.::
 Worm   375 RCVDWWGVGVVMYEMMCGRLPF--YSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQ 437

  Fly   286 RFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFD 334
            |.|.......:|...::|:.|:|.....:.:..||.||:.:..|.|.||
 Worm   438 RLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFD 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	111/299 (37%)
akt-1	NP_001023646.1	PH_PKB	14..121	CDD:269947
		STKc_PKB	197..525	CDD:270723	110/293 (38%)