Protein Alignment CG12069 and air-1

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_505119.1
• Gene: air-1 / 179202
• WormBaseID: WBGene00000098
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 283
• Identity: 87/283 - (30%)
• Similarity: 150/283 - (53%)
• Gaps: 19/283 - (6%)

  Fly    44 LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMS-EKNVLRSMTFPNT 107
            |||:::...||.|.||.|.:.||:::....|.|.|.|.|:::. .|||.:. |..:...:..||.
 Worm    41 LDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQL-GVSHQLKREIEIQYHLRHPNI 104

  Fly   108 VNLIASYKDFDSLYLVLPLIGGGELFT--YHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRD 170
            :.|...:.|...::::|.....||||.  ..:...|..|..|..:..|:..||.|.|...:::||
 Worm   105 LTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRD 169

  Fly   171 LKPENIMMDKNGYLKVTDFGFAKKVE-TRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFE 234
            :||||:::|....||:.|||::...: ::..|||||.:||.||::.::|:..:||.||.|:|:||
 Worm   170 IKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFE 234

  Fly   235 FVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKE 299
            .:.|::||:....|  .:..:|.|....:||..:.....|::.:::.:..:|...:     ||..
 Worm   235 MLVGYAPFANQTGD--KLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLV-----DIMA 292

  Fly   300 HEWFK------DVEWIPLLNQTV 316
            |.|.|      |:| :||...|:
 Worm   293 HPWIKEMKQREDIE-VPLFISTL 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	86/282 (30%)
air-1	NP_505119.1	STKc_Aurora	43..297	CDD:270909	79/261 (30%)