Protein Alignment CG12069 and pkc-3

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_495011.1
• Gene: pkc-3 / 173914
• WormBaseID: WBGene00004034
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 313
• Identity: 104/313 - (33%)
• Similarity: 173/313 - (55%)
• Gaps: 24/313 - (7%)

  Fly    41 STGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMT-F 104
            :..|:|:.:...:|.||:.||.......:...||.|.:.|:...:.:.:..|.:||:|..:.: :
 Worm   247 AVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNY 311

  Fly   105 PNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYR 169
            |..|.|.:.::....|:.|:..:.||:|..:.::.||..|:.||||:.::.|||.:||...::||
 Worm   312 PFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRGIIYR 376

  Fly   170 DLKPENIMMDKNGYLKVTDFGFAK---KVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVL 231
            |||.:|:::|..|::|:||:|..|   |....|.|.||||.|:.|||::...||.||||||.|||
 Worm   377 DLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVL 441

  Fly   232 VFEFVAGHSPFSAHNRDVMSMYNK-----------ICEADYKMPSYFSGALRHLVDHLLQVDLSK 285
            :||.:||.|||     |::.|.|.           |.|...::|...|.....::...|..|.::
 Worm   442 MFEMMAGRSPF-----DIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTE 501

  Fly   286 RFG---NLINGNRDIKEHEWFKD-VEWIPLLNQTVNAPYVPNISNPEDISNFD 334
            |.|   ::..|.||:|||::|:. ::|..|..:.|..||.|.:.:..|:::||
 Worm   502 RLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFD 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	103/309 (33%)
pkc-3	NP_495011.1	PB1_aPKC	13..95	CDD:99725
		C1_aPKC	126..180	CDD:410344
		STKc_aPKC	257..586	CDD:270740	102/303 (34%)