Protein Alignment CG12069 and Akt

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_308030.6
• Gene: Akt / 1269396
• VectorBaseID: AGAMI1_008154
• Length: 570
• Species: Anopheles gambiae
• Alignment Length: 356
• Identity: 125/356 - (35%)
• Similarity: 194/356 - (54%)
• Gaps: 24/356 - (6%)

  Fly    22 LDKLRED--FNKK--FATNTPSPS----TGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQL 78
            :..:.||  .|:|  :.|.|...|    ..|:::|....||.|:||||.|.||:.|...||.|.|
Mosquito   193 MGSIAEDELVNEKPVYGTATDKVSGKRKVTLENFEFLKVLGKGTFGKVILCREKTSSKLYAIKIL 257

  Fly    79 SKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFT 143
            .||.|::..:|:|.|:|..||::...|..::|..|::..|.|..|:..:.|||||.:..:.|.|.
Mosquito   258 KKDVIIQKDEVAHTMAESRVLKTTNHPFLISLKYSFQTVDRLCFVMQYVNGGELFFHLSRERIFP 322

  Fly   144 EKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET---RTMTLCGT 205
            |.:.|||||::..||.|||...::|||||.||:::||:|::|:.|||..|:..|   .|.|.|||
Mosquito   323 EDRTRFYAAEIISALGYLHSHGIIYRDLKLENLLLDKDGHIKIADFGLCKEDITYGRTTKTFCGT 387

  Fly   206 PEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGA 270
            ||||.||:::...||.:||||..||:::|.:.|..||  :|||...::..|...:.|.|...|..
Mosquito   388 PEYLAPEVLEDNDYGHAVDWWGTGVVMYEMICGRLPF--YNRDHDILFTLILMEEVKFPRNISPN 450

  Fly   271 LRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDK 335
            .|.|:..||..:..:|.|...:..::|..|.:|..:.|..|:.:.:..|:.|.:::..|...||:
Mosquito   451 ARSLLSGLLVKNPKQRLGGGPDDAKEIMAHPFFASINWTDLVQKRITPPFKPQVTSDTDTRYFDR 515

  Fly   336 ----------VSDKPRPKAKTMRHEEAFADF 356
                      .||...|.. .::.|..|::|
Mosquito   516 EFTGESVELTPSDSNGPLG-AIQEEPHFSEF 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	110/292 (38%)
Akt	XP_308030.6	None