Protein Alignment CG12069 and Rps6ka2

DIOPT Version :10

• Sequence 1: NP_651819.1
• Gene: CG12069 / 43643
• FlyBaseID: FBgn0039796
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_038934903.1
• Gene: Rps6ka2 / 117269
• RGDID: 620676
• Length: 762
• Species: Rattus norvegicus
• Alignment Length: 338
• Identity: 119/338 - (35%)
• Similarity: 187/338 - (55%)
• Gaps: 26/338 - (7%)

  Fly    16 VDYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRE---RESGVYYASKQ 77
            |..|.|...::|.|.|      ..||    .:|:...||.||:|||.|||:   .::|..||.|.
  Rat    67 VKEIDISSHVKEGFEK------ADPS----QFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKV 121

  Fly    78 LSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKF 142
            |.|..:....:|...| |:::|..:..|..|.|..:::....|||:|..:.||:|||...|...|
  Rat   122 LKKATLKVRDRVRSKM-ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMF 185

  Fly   143 TEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV---ETRTMTLCG 204
            ||:..:||.|::.|||::||...::|||||||||::|:.|::|:||||.:|:.   :.|..:.||
  Rat   186 TEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCG 250

  Fly   205 TPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNR-DVMSMYNKICEADYKMPSYFS 268
            |.||:.||::..:.:..|.|||:||||:||.:.|..||...:| :.|::   |.:|...||.:.|
  Rat   251 TIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL---ILKAKLGMPQFLS 312

  Fly   269 GALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNF 333
            ...:.|:..|.:.:...|.|..::|..:||.|.:|..::|..|..:.:..|:.|.:..|||..:|
  Rat   313 AEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHF 377

  Fly   334 DKVSDKPRPKAKT 346
            |     |...|:|
  Rat   378 D-----PEFTART 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12069	NP_651819.1	Protein Kinases, catalytic domain	45..335	CDD:473864	107/296 (36%)
Rps6ka2	XP_038934903.1	STKc_RSK_N	92..408	CDD:270734	110/303 (36%)
		STKc_RSK3_C	440..732	CDD:271080